Will a lightning supercharger fit a a 2001 f150 4.6.

 

HI!... No the 5.4 has a taller deck height than the 4.6, so that translates into the 5.4 is wider between the valve covers than the 4.6. Thus, the 5.4 lower intake manifold for the SC will be too wide for your 4.6 block.