Yes, to keep the seals lubed. A few times during the winter should do it. May have to do it on a warmer day, or right after its been run hot and parked, or just out of a garage if it was warmer. Otherwise, the low temp cutout won't let the A/C actually run. Cutouts are roughly in the upper 30's F.

 

Is it recommended that I run the A/C periodically to keep the system lubed? It's winter time here for the next time 5-6 months anyway.....