This started about two weeks ago. I'm driving down a "bumpy" road, almost everywhere in Minnesota, and all my doors unlock and the inside lights come on. Then the lights go off and the doors lock again. This only happens on really bumpy roads. Could I have a door latch malfunctioning? I can go for several days without a problem and then is it happen again. Any ideas?

 

the door switches may be acting up.
try lubing them with WD40. see this link.....
https://www.f150online.com/forums/sh...hreadid=193352

 

Just a thought but my truck I found has weight sensors in the front seats.
Maybe your side is opening and closing when the bumps move you while driving.