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When my truck was stock (with stock tires) I got around 13-14 or so city and 21 highway. People hated driving with me on the highway though, No AC and no more than 65mph.
In an attempt to get a better idea of where I stand. Let me be a bit more specific.
My truck is an :
05 Screw 4x4 5.4L. 86K miles
K&N Drop in
Stock wheels and tires
Flowmaster muffler SISO (came with truck when I bought it)
I was getting around 15 MPG back when everything was completely stock and boring. Now I get around 17.5 during the summer, but I'm sure it's going to drop to around 16.5 when the winter blends are released.