Sorry, I've been travelling the past couple of days. Still no light on the instrument cluster, even when the fuse was showing power.
I've also added some dielectric grease to each blade of the fuse to hopefully improve the connection

 

I also discovered that the horn isn't working either.

 

Sorry, I've been offline for a while. The exhaust manifolds needed to be replaced on the truck, so the instrument panel got put on the back burner. Just finished the manifolds, and I'm ready to get back to the instrument panel. Any suggestions?

 

So what was the fix? I have this same issue with my truck.

 

Hello, I was wondering what the fix ending being. I have 2000 F150 XLT Super Crew and I’m having the same problem. The speedometer and the tachometer lights do not work in my cluster. Check the bulbs and they’re good. The cruise control button on steering wheel doesn’t light up. The A/C controls doesn’t light up either. Also the lock switch and window switch on the drivers and passenger doors don’t light up as well.

 

Did you make ANY of the checks recommended to the OP who had the same issue?