Will 17" rims from a 2005 F150 fit the 2001 F150 that has 16" rims on it? Will I need to do anything major to the truck or just remove and install with no adjustments? The tires going on are 245/70R17. Current tire is 235/70R16.

 

Nope, different bolt pattern. 2001 is 5 lug, 2005 is 6 lug. The only 17" wheels that will fit a 2001 were an option on 1997-2003 trucks.