2014 5.0 misfire all cylinders
 

Have a 2014 F150, 5.0, 4x4 with approx 250k on it. Just changed plugs and COP's 2 weeks ago.

Truck has started to run like CRAP!! Has terrible miss to it. At idle it misses a little bit. When you try to accelerate, it's really bad. Ran ForScan on the truck. I have NEVER seen so many codes on 1 vehicle....
P0300, P0301, P0302, P0303, P0304, P0305, P0306, P0307, P0308, P0310
Then i got codes for TPMS, HVAC and a few other issues. My main concern is the engine missing. Can anyone give me a good idea of where to start on what would cause a miss on all cylinders?

Any pointers would definitely be appreciated!!

First off, happy Thanksgiving...

This sounds more electrical than anything.

Check your grounds for corrosion. Along with the fuse boxes for water ingress or corrosion. This also includes looking at the wiring for chaffing or gnawed wires from an infestation such as rodents, squirrels, chipmunks and the like.

I would also recommend having your battery and alternator tested at your local auto parts store as this can cause ECU problems.

You also say that you replaced the plugs and coils 2 weeks ago. Did you use any dielectric grease in the boots?

Lastly, what kind of coils and plugs did you use? Did you double-check the gap and torque to spec?