TOLEDO, Ohio — Five members of a Maryland family were killed late Sunday when a pickup truck driven by an alleged drunk driver slammed into their minivan, MyFOXToledo.com reports.

Bethany Griffin, 36, and her daughters — Jordan Griffin, 10, Haley Burkman, 10, Lacie Burkman, 7, and Vadi Griffin, 6 months — were killed when the pickup hit their vehicle on Interstate-280, just north of downtown Toledo.

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The family's father, Danny Griffin, and two other children survived, the station reports.

Michael Gagnon, 24, of Adrian, Mich., was driving northbound in the southbound lanes of I-280 when his black Ford F350 collided with the Griffins' white Chevy Astro minivan, MyFOXToledo.com reports.

"It was among the worst I've seen," Assistant Fire Chief Luis Santiago said of the crash scene. Bits of gift wrap and toys were strewn about the highway, suggesting the minivan was carrying members of a family heading home from visiting relatives for the holidays, he added.

Griffin and the two other children from the minivan were taken to the hospital with life-threatening injuries, Santiago said. The driver of the pickup also was taken to a hospital, but his injuries did not appear as serious.

The accident occurred around 11 p.m. when the minivan, traveling in the southbound lanes on Interstate 280 near the I-75 interchange, collided with the truck, going in the opposite direction, Santiago said.