I have a 2007 f150 supercrew 4x4 with the 5.4liter and auto trans. I have 65,000 miles on it now and this problem started the very same day as i emissions test which is just a coincidence. and I am out of warranty.

After warming up the truck will jerk multiple times on steady throttle and a slight increase in throttle, on level ground and inclines, never on downhill.

i have a superchip programmer that came with my truck when i bought it new in 07, the code is P0300 and is a random multiple misfire with no specific cylinder tagged.

Seeing that it was random i decided to replace the cheaper parts first that would effect multiple cylinders first, so i replaced both Camshaft senors and crankshaft sensor, with no effect, i then replaced all 8 cops and spark plugs with no effect ( left the plugs in and took the cops back ) I have looked at every vacuum line coming off the engine for cracks and tears and nothing, i removed the entire intake system from the throttle body to the air filter and replaced the TB seal and cleaned and reassembled it with no effect.

so i decided to monitor my o2 sensors and noticed that B1-S1 and S2 and B2-S1 Change voltages dramatically from .01 up to .9 and B2-S2 stays steady at .742.
I don't know if this is normal or not so at this point i am lost and open to any good ideas that y'all can come up with.