I would say it's easier on the modular engines than the old small block Ford. Access on a truck isn't that bad, but probably not as easy as a mustang. It's more of a reach and height issue. I would try torquing the bolts on the manifold first before changing gaskets. It would be hard for this style of gasket to leak. A loose intake is a possibility, but I'd look for a broken vacuum line or vacuum line that is not plugged into an open port.
2008 F-150 Lariat SuperCharged SuperCrew 4x4